Wimbledon, England (Sports Network) - Seven-time champion Roger Federer was a shocking second-round loser on a bizarre Wednesday at Wimbledon. Ukrainian Sergiy Stakhovsky, ranked 116th in the world, stunned the third- seeded former world No. 1 star and reigning titlist in four sets, 6-7 (5-7), 7-6 (7-5), 7-5, 7-6 (7-5), on the famed Centre Court at the All England Club. The stunner came just two days after 135th-ranked Belgian Steve Darcis shocked two-time Wimbledon champ and reigning French Open king Rafael Nadal on the hallowed lawns. Displaying some classic serve-and-volley tennis, Stakhovsky baffled Federer for most of the match and dazzled the Swiss icon with some outstanding shot- making on Day 3. Stakhovsky ultimately converted on his second match point when the 31-year-old Federer misfired wide on one final backhand. The 27-year-old Stakhovsky had been 0-20 in his previous matches against top-10 players. He was a first-round loser in his last four Grand Slam events prior to this fortnight. Federers record streak of reaching 36 consecutive Grand Slam quarterfinals came to an end. This was his earliest exit at a Grand Slam since a first-round loss at the 2003 French Open. The amazing Federer hadnt lost to a player outside the top 100 since 2005 (Richard Gasquet) and this was the earliest exit by a defending champion at Wimbledon since Lleyton Hewitt lost in the opening round in 2003. The 17-time Grand Slam king Federer beat Andy Murray in last years Wimbledon finale to tie Pete Sampras for the most mens titles here in the Open Era. Meanwhile, the heavy British crowd favorite Murray eased into the third round, while no less than five men succumbed to injuries on Day 3, including sixth-seeded French star Jo-Wilfried Tsonga. The second-seeded Murray managed to avoid the Day-3 carnage with a 6-3, 6-3, 7-5 handling of overmatched Taiwanese Yen-Hsun Lu on Court 1. Murray was last years Wimbledon runner-up to Federer and then beat the Swiss great in last years Olympic gold-medal match here at the AEC. The British star is the reigning U.S. Open champ and was this years Australian Open runner-up to current world No. 1 Novak Djokovic. The 26-year-old Murray is trying to give Britain its first mens Wimbledon singles champion in 77 years. The former Aussie Open runner-up Tsonga, who reached Wimbledon semifinals each of the last two years, was trailing capable Latvian Ernests Gulbis 3-6, 6-3, 6-3 when he quit because of an apparent knee issue on an injury-filled Wednesday. Meanwhile, 10th-seeded recent Queens Club grass-court runner-up Marin Cilic was scheduled to meet Frenchman Kenny De Schepper, but decided against playing due to a left knee injury, while 6-foot-10 18th-seeded American John Isner was battling Frenchman Adrian Mannarino when he retired at 1-1 in the first set, also citing a left knee injury. "I would say (its a) very black day," Cilic said of all the injury withdrawals. "The other days, other weeks, there were no pullouts. Everything just happened today." Isner hurt his knee early in his match against Mannarino, took an injury timeout and called it quits after two games. The towering American, of course, is best known at the All England Club for playing the longest match in tennis history three years ago with a five-set marathon in the first round against Nicolas Mahut. The 11-hour, 5-minute epic took three days to complete because of rain and darkness, ending with a 70-68 score in the final set. Fifteenth-seeded Spaniard Nicolas Almagro steered clear of any problems by holding off Frenchman Guillaume Rufin 7-5, 6-7 (6-8), 6-3, 6-4. Also pulling out were the other giant-killer Darcis and Czech veteran Radek Stepanek. Darcis posted one of the biggest upsets in Wimbledon history on Monday when he shocked Nadal in straight sets. But he was unable to face Polands Lukasz Kubot because of a right shoulder injury on Wednesday. "Had to withdrawn after a win like this!?THE most difficult thing i had to do!!!#triedeverythingtoplaybutdidntwork!!!!" Darcis wrote on his Twitter account. Stepanek was losing to 6-foot-8, 24th-seeded Pole Jerzy Janowicz 6-2, 5-3 when he retired from their match due to a thigh injury. Veteran 20th-seeded Russian Mikhail Youzhny overcame promising Canadian Vasek Pospisil 6-2, 6-7 (3-7), 7-6 (9-7), 3-6, 6-4; 22nd-seeded Argentine Juan Monaco came back to beat American Rajeev Ram 5-7, 6-2, 6-4, 6-2; rising 25th- seeded Frenchman Benoit Paire subdued fellow countryman Stephane Robert 6-4, 7-5, 6-4; Spanish left-hander Fernando Verdasco erased 31st-seeded Frenchman Julien Benneteau 7-6 (7-1), 7-6 (7-4), 6-4; and 32nd-seeded former top-10 Spaniard Tommy Robredo bested the aforementioned Mahut 7-6 (7-3), 6-1, 7-6 (7-5). Also on Wednesday, Serb Viktor Troicki topped Russian Andrey Kuznetsov 6-4, 6-3, 6-4, Austrian southpaw Jurgen Melzer downed German Julian Reister 3-6, 7-6 (7-2), 7-6 (7-5), 6-2, and German Dustin Brown doused the 2002 Wimbledon champ and former world No. 1 Hewitt 6-4, 6-4, 6-7 (3-7), 6-2. "I cried like a little girl," Brown said after beating the two-time major champion Hewitt. The second round is scheduled to conclude on Thursday, including a match for the reigning Aussie Open champion and 2011 Wimbledon titlist Djokovic, who will take on American journeyman Bobby Reynolds. Other top-10 seeds on the Day-4 slate are No. 4 French Open runner-up David Ferrer, No. 7 2010 Wimbledon runner-up Tomas Berdych, No. 8 former U.S. Open champion Juan Martin del Potro, and No. 9 Frenchman Richard Gasquet. Milos Raonic of Thornhill, Ont., and Jesse Levine of Ottawa won their first-round matches earlier this week. Raonic next faces Igor Sijsling of the Netherlands, while Levine battles Argentinian Juan Martin del Potro. Levines match can be seen live on TSN.ca on Friday morning at approximetly 8am et/5am pt. Watch exclusive bonus online coverage throughout the competition on TSN.ca, including full coverage of select matches not being televised. Wholesale Custom 76ers Shirts . No. 13-seeded John Isner and No. 21 Philipp Kohlschreiber were among six players who dropped out of the tournament on Tuesday, joining No. 12 seed Tommy Haas and two other players who withdrew on Monday. 76ers Jerseys China . Neymar curled home a free kick from just outside the area to put the 2014 World Cup host ahead in the 44th minute. Three minutes after the break, a simple through pass from Paulinho freed Oscar and the Chelsea star rounded goalkeeper Jung Sung-ryong to extend Brazils lead. http://www.custom76ersjersey.com/ . Scott Kazmir allowed four hits in seven shutout innings, Michael Brantley hit a two-run homer in a three-run first inning and the Indians maintained their hold on an AL wild-card spot with a 4-1 win over the Houston Astros on Saturday night. Cheap Custom 76ers Jersey . Three came down to the fourth quarter while quarterbacks continued to shine in all four games; so important to the overall quality of the game. Custom Moses Malone Jersey . -- Stanford squashed Oregons national championship hopes again, schooling the Ducks in power football. MINNEAPOLIS -- Byron Buxton homered in his return to the majors, and Trevor Plouffe continued his resurgence with a two-run shot as the Minnesota Twins beat the Chicago White Sox 8-5 and ended a 13-game losing streak Thursday night.Minnesota got to Chicago starter Jose Quintana, who entered the day leading the American League with a 2.77 ERA. Quintana (11-10) allowed seven runs and seven hits in five innings and saw his ERA rise to 3.05.Ervin Santana (7-10) escaped trouble to win for the fourth time in five decisions. He gave up 11 hits and two walks, but allowed just two runs as the Twins snapped their losing streak, one off the franchise record for a season.Brandon Kintzler recorded his 13th save in 14 chances.Buxton started his third stint with Minnesota this season in surprising fashion, connecting for a three-run home run to cap a five-run second inning. The home run reached the second deck in left field and was Buxtons second of the season, his first in 34 games.The former top prospect has had a rough transition to the majors, hitting .199 entering Thursday in 109 career games the past two seasons. He was sent back to Triple-A Rochester on Aug. 7 after a 1-for-18 stretch saw his 2016 average dip to .193.Meanwhile, Plouffe has come around after a slow start to his season. He has hit .318 with three home runs and 16 RBI the past 16 games. Plouffe homered into the bullpens off Quintana in the fifth.Offense is a big reason the White Sox have gone 18-27 since the All-Star break. Chicago has scored 171 runs, the second-fewest in the league, since the break.The White Sox left runners in scoring position in each of the first five innings and left a total of 13 men on base in the game. Avisail Garcia snapped his bat over his knee in frustration after his second strikeout of the game in the seventh.Chicagos Todd Frazier hit his 34th home run to open the scoring in the second, and Jose Abreu connected for a two-run homer, his 20th, in the sixth.ddddddddddddCOME ON UPBuxton was Minnesotas lone call-up on Thursday with rosters expanding in September.Chicago added RHP Juan Minaya and C Kevan Smith from Triple-A Charlotte.Minaya, 25, was 5-6 with a 3.63 ERA and 47 strikeouts in 52 innings over 47 relief appearances since being claimed off waivers from Houston on June 22.Smith, 28, was recalled by the White Sox in April before going on the DL with a sacroiliac joint dysfunction without playing in a game. Smith was hitting .219 with eight home runs and 24 RBI for Charlotte this season.Minaya and Smith made their major league debuts in the eighth inning. Minaya pitched a scoreless inning. Smith lined out to center in his first at-bat.TRAINERS ROOMWhite Sox: SS Tim Anderson left the game in the third with a bruised right calf and was announced by the team as day to day. He was hit by line drive by teammate Melky Cabrera in the first. ... RHP Miguel Gonzalez (strained right groin) started a rehab assignment with Triple-A Charlotte on Thursday. Gonzalez took the loss while allowing seven runs -- six earned -- in 4 1/3 innings. He struck out seven.Twins: Pitchers Trevor May (low back strain) and Tommy Milone (left biceps tendinitis) each threw a bullpen session on Wednesday and are scheduled to throw in the bullpen again during the weekend. If all goes well, the two would make a simulated start sometime next week, Twins manager Paul Molitor said.UP NEXTRHP Kyle Gibson (5-8, 5.17 ERA) will start the second game of the four-game series for Minnesota on Friday against LHP Carlos Rodon (5-8, 3.91). Gibson has allowed nine earned runs over his past two starts but has given up just one earned run in 12 2/3 innings against the White Sox this season. Rodon has won his last three decisions and owns a 1.47 ERA in his past five starts. ' ' '